Key reasons provided by the 22 AGs:

First Reason:

“Under proposed IHR amendments and the Pandemic Treaty, however, the WHO’s Director-General would achieve the power to unilaterally declare a “public health emergency of international concern” (PHEIC) in one or more member nations. Such declarations can include perceived or potential emergencies other than pandemics, including climate change, immigration, gun violence, or even “emergencies” involving plants, animals, or ecosystems.”